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[PubMed: 2678202] Klesges RC, Mizes JS, Klesges LM

Recent studies have indicated that UBA52 expression is elevated in PASMCs under hypoxic conditions, exacerbating mitochondrial dysfunction by targeting the degradation of apoptosis-inducing factor (AIF) while simultaneously increasing cellular glycolysis and ROS release

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Tonally, "Courage Under Fire" feels like a courtroom drama without the courthouse and a ghost story without a specter, with Ryan haunting every frame as a fallen hero in the middle of a bloody cover-up